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Following an immune response, some cells of the B cell clone will remain dormant. They are able to respond to antigens encountered in the future. These cells are called __________ cells.

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memory

What cell type found in lymph nodes engulf and destroy damaged cells, foreign substances, and cellular debris?


A) Macrophages
B) Lymphocytes
C) Mast cells
D) Plasma cells

E) B) and C)
F) A) and D)

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The structure of a lymphatic vessel is most similar to what type of blood vessel?


A) Artery
B) Arteriole
C) Vein
D) Capillary
E) Metarteriole

F) A) and E)
G) C) and E)

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The function of the thymus is to destroy older, worn out red blood cells.

A) True
B) False

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After being bit by a poisonous snake, Jacob was treated with an injection of an antiserum produced by immunizing a horse or sheep with snake venom. What type of immunity does this provide for him?


A) Naturally acquired active immunity
B) Naturally acquired passive immunity
C) Artificially acquired active immunity
D) Artificially acquired passive immunity

E) A) and D)
F) C) and D)

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What is an example of an autoimmune disease?


A) Anaphylaxis
B) Acquired immune deficiency syndrome
C) Tissue rejection reaction
D) Systemic lupus erythematosus

E) A) and B)
F) A) and C)

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D

Select the example of a specific (adaptive) defense mechanism.


A) Phagocytosis
B) Inflammation
C) Immunity
D) Fever

E) B) and D)
F) B) and C)

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An upper respiratory infection is often associated with inflammed __________ lymph nodes.


A) cervical
B) inguinal
C) abdominal
D) thoracic

E) A) and D)
F) B) and C)

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Of the following lymphatic tissues/structures, the immune cells found in __________ are the most likely to initiate an immune response against food-borne pathogens.


A) mucosa-associated lymphoid tissue (MALT)
B) the spleen
C) lymph nodes
D) the thymus

E) C) and D)
F) None of the above

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A small molecule called a(n) __________ that on its own cannot stimulate an immune response, might become detectable to the immune cells once it combines with a larger molecule.


A) hapten
B) antigen
C) immunoglobulin
D) cytokine

E) A) and B)
F) A) and C)

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Colleen works in retail and is typically on her feet most of each of her 8-hour shifts. When she gets home, she complains about how swollen her feet and ankles are. Why does elevating her feet help to relieve the swelling?


A) Gravity assists the flow of lymph from the lower extremities back toward the trunk.
B) The increased blood flow to the elevated feet will help "wash" away the accumulated fluid.
C) The increased blood pressure in the elevated feet will reduce the formation of tissue fluid.
D) As blood pressure is reduced in the feet and ankles, more fluid is pushed from the circulation out into the tissues, causing more lymph formation.

E) B) and C)
F) C) and D)

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How do cytotoxic T cells destroy cancer cells and virally infected cells?


A) Their release of perforin puts holes in target cell's membranes.
B) They insert themselves into the target cell's membrane, lysing the cell.
C) They release cytokines that enter the target cell and destroy its nucleus.
D) They produce antibodies that attack the target cell, killing it.

E) None of the above
F) A) and B)

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What cell types are required for a normal immune response to occur?


A) Macrophages only
B) T cells only
C) B cells only
D) Both T and B cells

E) A) and D)
F) B) and C)

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Active immunity results when a person has an immune response to a pathogen causing a disease or infection.

A) True
B) False

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After a visit with her niece who had an active upper respiratory infection, Emma was worried that she would become ill as well. After a week, she still had no symptoms. What might explain Emma's response to exposure to this respiratory virus?


A) This was her first exposure, and her immune system underwent a primary immune response.
B) She had been exposed to this virus before. Her immune system underwent a secondary immune response.
C) She had been exposed to this virus before. Her immune system underwent a hypersensitivity response.

D) A) and B)
E) A) and C)

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Carl has frequent infections and, after testing, has been diagnosed with a genetic form of agammaglobulinemia (meaning no gamma globulins in the blood) . Why would this condition result in difficulty fighting off infections?


A) His B cells can't make antibodies, so he has no humoral immune response.
B) His T cells over-react, resulting in activation of autoantibodies.
C) His macrophages are overproducing cytokines, making the immune response ineffective.
D) He is unable to produce T cells, so he has no cellular immune response.

E) A) and D)
F) A) and B)

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What is the stimulus for production of interferons?


A) Chemical irritants
B) Viruses or tumor cells
C) Bacterial infection
D) Malarial parasites

E) B) and C)
F) B) and D)

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A(n) __________ is an injection containing an antigen that stimulates a primary immune response but that does not produce symptoms of the disease.

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vaccine

Activation of complement proteins results in several effects, including opsonization. What is opsonization?


A) Enhancing phagocytosis of antigens
B) Clumping of antigen-bearing agents
C) Attracting macrophages and neutrophils to the area
D) Rupturing the membranes of foreign cells

E) C) and D)
F) B) and D)

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Allison has severe hay fever. What is the mechanism for her hypersensitivity?


A) IgE antibodies bound to mast cells bind an allergen. Histamine and other mediators are released, causing symptoms.
B) Allergens combine with antibodies, forming complexes that deposit in tissue and cause tissue damage.
C) T cells become activated after repeated exposure to an allergen. Chemical mediators are released about 24 hours later, resulting in inflammation of the skin.
D) Autoantibodies attack "self" cells and tissues, resulting in inflammation and tissue damage.

E) C) and D)
F) A) and B)

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